![]() ![]() We also tested Spearman’s correlations between FGF-21 serum levels and biochemical and clinical metabolic parameters. Methods: Total and intact serum FGF-21 concentration was measured with an ELISA assay respectively in 51 and 46 subjects, comparing FGF-21 levels in dysmetabolic conditions. In this observational study, we analysed a group of subjects with metabolic disorders to unravel the putative link between visceral adiposity and FGF-21 serum levels. Objective: Increased Fibroblast Growth Factor-21 (FGF-21) circulating levels have been described in obesity. 3National Institute for Biostructures and Biosystems (INBB), Rome, Italy.2Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden. ![]() ![]() 1Department of Interdisciplinary Medicine, University of Bari “Aldo Moro”, Bari, Italy.Lucilla Crudele 1†, Oihane Garcia-Irigoyen 1,2†, Marica Cariello 1, Marilidia Piglionica 1, Natasha Scialpi 1, Marilina Florio 1, Giuseppina Piazzolla 1, Patrizia Suppressa 1, Carlo Sabbà 1, Raffaella Maria Gadaleta 1*‡ and Antonio Moschetta 1,3*‡ ![]()
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